单元网络教学法在生物化学教学中的应用

在生物化学教学中采用单元网络教学法 ,构建了生物化学课程单元网络图 ,并为了配合该教学法 ,编写了《生物化学学习指导》一书 .经过几年的教学实践 ,取得了良好的教学效果     

Fibulin-5/DANCE is essential for elastogenesis in vivo.

The elastic fibre system has a principal role in the structure and function of various types of organs that require elasticity, such as large arteries, lung and skin. Although elastic fibres are known to be composed of microfibril proteins (for example, fibrillins and latent transforming growth factor (TGF)-beta-binding proteins) and polymerized elastin, the mechanism of their assembly and development is not well understood. Here we report that fibulin-5 (also known as DANCE), a recently discovered integrin ligand, is an essential determinant of elastic fibre organization. fibulin-5-/- mice generated by gene targeting exhibit a severely disorganized elastic fibre system throughout the body. fibulin-5-/- mice survive to adulthood, but have a tortuous aorta with loss of compliance, severe emphysema, and loose skin (cutis laxa). These tissues contain fragmented elastin without an increase of elastase activity, indicating defective development of elastic fibres. Fibulin-5 interacts directly with elastic fibres in vitro, and serves as a ligand for cell surface integrins alphavbeta3, alphavbeta5 and alpha9beta1 through its amino-terminal domain. Thus, fibulin-5 may provide anchorage of elastic fibres to cells, thereby acting to stabilize and organize elastic fibres in the skin, lung and vasculature.     

“广西建设科技成果数据库”的特点及其应用

从数据库的构成、文献的标引著录、硬件配置及软件程序设计等方面对数据库所具备的各个特点，作了较详细的分析介绍。并列出检索应用实例。     

分子生物学设计性实验与七年制学生能力培养

通过分子克隆设计性实验,充实学生的基础理论和基本技术,引导学生独立设计实验、查阅资料解决存在的问题,促进医学专业七年制学生的能力培养.     

多环节冲击测量系统方波响应时间的计算

实际的冲击高电压测量系统，通常由多个不同特性的环节组成．作者以最简洁的数学推导式，表达了多环节测量系统方波响应时间的计算方法。借助于这一计算方法．讨论了方波源波形非理想时，它对实际方波响应时间测量值的影响。所提出的反映原始方波质量的技术指标，可比“上升时间”更易确定，而且实用性强．     

体育培养学生创新和实践能力研究

本文通过对学生创新能力的研究，探讨学生创新能力的内涵，揭示目前培养学生创造力在体育教学中存在的问题，寻求培养学生创新能力的途径和方法，提出教学改革的设想。     

一种用于自动标引系统的主题词自动切分方法

该文着重介绍一种知识指导下的主题词自动切分方法，该方法能灵活处理自然主题词、大幅度跳跃及关联词的切分问题，其字面切分精度达９９．３３％，综合切分精度达９８．９１％。     

非线性退缩抛物型方程组初边值问题的可解性

应用上、下解方法证明非线性退缩抛物组初边值问题当1相似文献